Riassunto

Purpose To review epidemiologic studies on risk of pancreatic cancer and occupational exposure to diesel exhaust.

Methods A literature search was conducted, and data were abstracted in a systematic fashion. Comparable results were combined using a random-effects meta-analysis.

Results Twenty-six studies were included in the review, including five studies based on routine statistics, 11 case–control studies [meta-relative risk (RR) of three estimates for diesel exhaust exposure 0.9; 95 % confidence interval (CI) 0.5, 1.6] and ten cohort studies (meta-RR of their results: 1.03; 95 % CI 0.93, 1.13). Few studies reported results according to duration of exposure or other quantitative measures; no consistent pattern emerged.

Conclusions The overall evidence from studies on occupational exposure to diesel exhaust and risk of pancreatic cancer leads to the conclusion of the absence of such association.

Keywords

Diesel exhaust, epidemiology, Pancreatic cancer

Articoli correlati che potrebbero interessarti

Reul Nicholas K., Li Wenjin, Gallagher Lisa G., Ray Roberta M., Romano Megan E., Gao Daoli, Thomas David B., Vedal Sverre MD, Checkoway Harvey

Risk of Pancreatic Cancer in Female Textile Workers in Shanghai, China, Exposed to Metals, Solvents, Chemicals, and Endotoxin: Follow-Up to a Nested Case-Cohort Study

Journal of Occupational and Environmetal Medicine. Vol. 58, Iss. 2, February 2016

M. Kreuzer, F. Dufey, D. Laurier, D. Nowak, J. W. Marsh, M. Schnelzer, M. Sogl, L. Walsh

Mortality from internal and external radiation exposure in a cohort of male German uranium millers, 1946–2008

Vol. 88, Iss. 4, May 2015

Adrian Loerbroks, Raphael M. Herr, Jian Li, Jos A. Bosch, Max Seegel, Michael Schneider, Peter Angerer, Burkhard Schmidt

The association of effort–reward imbalance and asthma: findings from two cross-sectional studies

Vol. 88, Iss. 3, April 2015