Rassegna bibliografica

Journal of Occupational and Environmetal Medicine. Vol. 57, Iss. 4, April 2015

Bladder Cancer Screening in Aluminum Smelter Workers


Objective: To present results of a bladder cancer screening program conducted in 18 aluminum smelters in the United States from January 2000 to December 2010.

Methods: Data were collected on a cohort of workers with a history of working in coal tar pitch volatile exposed areas including urine analysis for conventional cytology and ImmunoCyt/uCyt+ assay.

Results: ImmunoCyt/uCyt+ and cytology in combination showed a sensitivity of 62.30%, a specificity of 92.60%, a negative predictive value of 99.90%, and a positive predictive value of 2.96%. Fourteen cases of bladder cancer were detected, and the standardized incidence ratio of bladder cancer was 1.18 (95% confidence interval, 0.65 to 1.99). Individuals who tested positive on either test who were later determined to be cancer free had undergone expensive and invasive tests.

Conclusions: Evidence to support continued surveillance of this cohort has not been demonstrated.


Aluminum Smelter Workers, Bladder cancer, screening program

Articoli correlati che potrebbero interessarti

Screening for bladder cancer with urinary tumor markers in chemical workers with exposure to aromatic amines

Vol. 87, Iss. 7, October 2014

Bladder cancer incidence among workers exposed to o-toluidine, aniline and nitrobenzene at a rubber chemical manufacturing plant

Vol. 71, Iss. 3, March 2014

Cancer incidence among workers occupationally exposed to dinitrotoluene in the copper mining industry

Vol. 87, Iss. 2, February 2014